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Childbirth Medications Research

This is the package insert for Cervidil. It lists the risks and contraindications.

This is the package insert for Cytotec. It lists the risks and contraindications.

Sublimaze is a pain medication for labor.

Bupivacain is a pain medication for labor.

Nubain is a pain medication for labor.

Hughes D, Simmons SW, Brown J, Cyna AM. Combined spinal-epidural versus epidural analgesia in labour (Cochrane Review)
This review begins with the following background information:

Traditional epidural techniques have been associated with prolonged labour, use of oxytocin augmentation, and increased incidence of instrumental vaginal delivery. The combined spinal-epidural (CSE) technique has been introduced in an attempt to reduce these adverse effects. CSE is believed to improve maternal mobility during labour and provide more rapid onset of analgesia than epidural analgesia.
After a review of the literature, the researchers have found that "There is no difference between CSE and epidural techniques with respect to: the incidence of forceps delivery, maternal mobility, PDPH, cesarean section rates or admission of babies to the neonatal unit."
The differences they did find were:
  • CSE provides faster onset of effective pain relief from the time of injection
  • CSE women experience more itch than women with a traditional epidural

Bennett, A., Hewson, D., Booker, E., & Holliday, S. (1985). Antenatal preparation and labor support in relation to birth outcomes. Birth, 12,9.
Women who received epidurals were less satisfied with thier childbirth experience.

Joseph Gambone, D.O. and Katherine Kahn, MD, "The Effect of Epidural Analgesia for labor on the cesarean Delivery Rate," Obstetrics and Gynecology 83, no. 6 (June 1994): 1045-1052.

Thorp, MD, et al., "Epidural Anesthesia and Cesarean Section for Dystocia: Risk Factors in Multiparas." American Journal of Perinatology 8, no. 6: 402-410.

Thorp, Md, et al., "The Effect of Intrapartum Epidural Analgesia on Nulliparous Labor: A Randomized, Controlled, Prospective Trial," American Journal of Obstetrics and Gynecology 169, no. 4: 851-858.

"The Effects of maternal Epidural Anesthesia on Neonatal Behavior During the First Month," Developmental Medicine and Child Neurology, 1992.

G.A. Albright, Anesthesia in Obstetrics: Maternal, Fetal, and Neonatal Aspects (Menlo Park, CA: Addison-Wesley, 1978)

"The Effect of Lumbar Epidural Analgesia on the Rate of Cervical Dilation and the Outcome of Laobr of Spontaneous Onset," British Journal of Obstetrics and Gynecology (1980):87.

"The Influence of Maternal Analgesia on Neonatal behavior: Epidural Bupivacaine," British Journal of Obstetrics and Gynecology (1981): 87.

"Obstetric Consequences of Epidural analgesia in Nulliparous Patients," Lancet (1971): 7708.

"Lumbar epidural Analgesia in Labour: Relation to Fetal Malpositioning and Instrument Delivery," British Medical Journal (1977): 1.

"The Effect of Continuous Lumbar Epidural Analgesia in the Acid-Base Status of Maternal Arterial Blood During the first Stage of Labour," Journal of Obsterics and Gynecology British Common, (1973): 80.

"Regional Obstetric anesthesia and newborn Behavior: Effect Over the First Ten Days of Life." Pediatrics (1976): 58.




What would you like next?

Read some Sample Birth Plans and get information to help put your birth plan together.

Find out about ways to reduce unnecessary pain in labor.

Learn ways to handle Childbirth Challenges.

Find out what normal labor is like.

Review the birth plan options that may be available to you.


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Most Recent Update: July 8, 2009
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